Vampires - Should burn, smoke or if left in sunlight for too long, die. not sparkle.and should be able to be killed by a stake through the heart, decaptiation repelled by holy water, crosses, garlic.
Don't exsist in RL outside of bats and bloodsucking paracites like fleas.
Werewolves, full moon shifters only, also are slightly humanoid when in 'wolf form.