Okies. I've only done a few item graphics in my life and I recieved a bit of training from Xee on how to do them as well. So here's what I've got to say
Your lines, they're generally all the same weight.It just looks a bit skinny and unprofessional in my opinion. I'm guessing you use the pen-tool (or some variation of it) amirite? Well, in my opinion (and it's only my opinion), the pen tool should be left to bigger things that will make the viewer's attention mainly focus on your colours and other details, not the lines. If you own a tablet, use the brush tool to create the lineart. It's kinda hard and takes a tad bit more time, but it's worth it.
Your shading's a bit dodgey. You've sort of got a fixed light source there, but it seems that you haven't really gotten to understand how light works yet. This can only improve with practice in my opinion. You're using too many shade layers. Two's enough in my opinion. Remember, leave your shading and base colour on separate layers. The shading la
yer should be on multiply so you can edit the brightness if it's too dark/ligth (hint: ctrl+U).
Highlights are important, use them
The actual drawing's a bit dodgey, your perspective's sort of weird and I think learning other drawing techniques (Crating, point-perspective) could help get it all right. But even so, nothing beats studying refs and practice. I also don't you should just focus doing item graphics only, you should always do larger things. It helps a bundle.
Oh and you should look at other people's item graphics, always helps when you're not sure what to do.