The purple alerts that tell us about the quest givers needing "help" are, for me at least, completely ignored at best and get in my way at worst. I don't think I've ever used them for anything even when they were first started and sometimes when they pop up they shift everything just far enough down the page that I either have to scroll or that my mouse isn't aligned with where I thought it would be. This is a minor inconvenience of course but considering they provide 0 value (and even still pop up when you're out of quest uses, making them deceitful) I don't see a reason we shouldn't be able to just turn them off.
Important note: since other alerts can happen at the same time as these, it should not affect the rate of any other alerts and I am not advocating for turning off individual alerts or making other alerts more common. JUST the purple "reminder" ones. If we're concerned about new users coming in and needing to see them (again, I never did but I can see how it might be useful for some people), then perhaps the option to turn off is best and it can default to on.